Remote presentation at the annual American Society of Tropical Medicine and Hygiene conference. Presented early work on the Deme Inbreeding Spatial Coefficient framework and the DISCent R-package. This project is currently in preparation.
BACKGROUND: COVID-19 has the potential to cause substantial disruptions to health services, due to cases overburdening the health system or response measures limiting usual programmatic activities. We aimed to quantify the extent to which disruptions …
BACKGROUND: Adults are frequently infected with malaria and may serve as a reservoir for further transmission, yet we know relatively little about risk factors for adult infections. In this study, we assessed malaria risk factors among adults using …
Coupling epidemiologic analysis with relatedness metrics (identity by descent) and population dynamics, we show that there is active transmission between Tanzania and Zanzibar
The Democratic Republic of the Congo (DRC) harbors 11% of global malaria cases, yet little is known about the spatial and genetic structure of the parasite population in that country. We sequence 2537 Plasmodium falciparum infections, including a …
This study examines the demography and population structure of Plasmodium falciparum in Tanzania and Zanzibar, highlighting the critical role of parasite importation in malaria elimination efforts. The findings have important implications for …
BACKGROUND: Tanzania's Zanzibar archipelago has made significant gains in malaria control over the last decade and is a target for malaria elimination. Despite consistent implementation of effective tools since 2002, elimination has not been …
This study examines cytochrome B mutations in Plasmodium falciparum among patients failing treatment with atovaquone-proguanil in Cambodia. Despite treatment failures, selection of cytochrome B mutants was rare, suggesting alternative mechanisms of …